The Role of Olive Tree Polyphenols In The Prevention of COVID-19: A Scoping Review Part 2
V. 174 N. 6 (2023), Review
V. 174 N. 6 (2023)

The Role of Olive Tree Polyphenols In The Prevention of COVID-19: A Scoping Review Part 2: doi: 10.7417/CT.2023.2481

Review
Pubblicato 2023-11-23
K. Dhuli
MAGI'S LAB
C. Micheletti
MAGI'S LAB, Rovereto (TN), Italy.
P.E. Maltese
MAGI'S LAB, Rovereto (TN), Italy.
B. Tanzi
MAGI'S LAB, Rovereto (TN), Italy.
S. Benedetti
MAGI'S LAB, Rovereto (TN), Italy.
S. Tezzele
MAGI'S LAB, Rovereto (TN), Italy.
C. Mareso
MAGI EUREGIO, Bolzano, Italy.
S.T. Connelly
San Francisco Veterans Affairs Health Care System, Department of Oral & Maxillofacial Surgery, University of California, San Francisco, CA, USA
F. Gaffuri
Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy
G.M. Tartaglia
Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy
S. Nodari
Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University and Spedali Civili of Brescia, Brescia, Italy
G. Arabia
Cardiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Ital
F. Fioretti
Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University and Spedali Civili of Brescia, Brescia, Italy
C. Calandri
M. Perrone
Department of Cardiology and CardioLab, University of Rome Tor Vergata, Rome, Italy
M. Bertelli
MAGISNAT, Peachtree Corners (GA), USA
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Parole chiave

SARS-CoV2
COVID-19 pandemic
polyphenols
antiviral
olive tree

Abstract

The recent COVID-19 pandemic caused by SARS-CoV-2 affected hundreds of millions of people and caused millions of deaths. There are few effective medications against SARS-CoV-2, and several studies attempted to make drugs based on natural components, such as olive leaves. Olive leaves are rich in polyphenolic compounds, which were proposed as a viable co-therapy supplement to treat and improve clinical symptoms in COVID-19 patients. Polyphenols have renown anti-inflammatory and multitarget antiviral effects on several virus families, which could be among the reasons of the beneficial effects of the Mediterranean diet against COVID-19. This scoping review is focused on the effect of olive tree polyphenols as a natural remedy to inhibit SARS-CoV-2, mainly discussing their influence on the process of viral entry into host cells by endocytosis.

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